Take any topic, something written about many times. Turn it upside down, give it a new spin, a fresh slant and look at it in a new and unexpected way. The best way to do this is to combine ideas, two different sides of a coin, two different opinions, two different ideas, etc. Unbalance something but combining it in a new way and turn it upside down.
Religion: Do atheists believe in reincarnation, if so, how do they think it works?
The Death Penalty: Should the death penalty be painful, like a punishment, or should it be impartial, like putting a dog to sleep?
Health Care: Should health care be free if it means hospitals will be run like factories focused on production rather than care?
Can you come up with other ideas which take a topic and turn it upside down?